Choleretic for pancreatitis: drugs and herbal remedies

Pancreatitis is a serious pathology that requires drug therapy. For this purpose, different groups of drugs are used, including choleretic agents.

Let us characterize some representatives of this category of drugs. Let's find out why a choleretic drug is prescribed for pancreatitis, how to take ursodeoxycholic acid, Odeston and herbal medicines Gepabene, Tykveol, Allochol and Chophytol for pancreatitis.

A little information

Pancreatitis is a pathological process localized in the pancreas, characterized by acute or chronic inflammation of pancreatic tissue. It develops due to the pathological influence of its own enzymes, caused by the retention of secretions inside the ducts as a result of their complete or partial overlap. Therefore, in the treatment of pancreatitis, medications aimed at eliminating the narrowing of the lumen are in demand. Choleretic substances have this ability.

Attention! The use of choleretic drugs is contraindicated in acute pancreatitis, including exacerbation of chronic pancreatitis.

Representatives of this group according to their mechanism of action are divided into 2 categories:

Choleretics – increase the release of bile.
Cholekinetics – increase the activity and tone of the bile duct, eliminate hypertonicity of the duct.

Most choleretic drugs combine both actions.

For pancreatitis, such drugs are prescribed to facilitate the removal of gland secretions into the small intestine.

According to the source of production, choleretic drugs are divided into 2 categories:

Plant origin (Tykveol, Hofitol, Allohol, Gepabene, gastrointestinal herbs, medicinal herbs containing bitterness - dandelion, wormwood, etc.).
Chemicals (ursodeoxycholic acid, Odeston).

General indications for the use of choleretic drugs, in addition to chronic inflammation:

cholecystitis;
symptoms of dyspepsia (pain in the right hypochondrium, epigastric pain, nausea, vomiting, abnormal stool);
liver diseases (cirrhosis, fibrosis, hepatitis);
pathologies of the stomach and intestines;
chronic kidney disease;
obesity;
anorexia;
biliary dyskinesia.

Contraindications:

acute cholecystitis, cholelithiasis;
acute biliary pathology;
severe liver dysfunction;
hypersensitivity to the components of the drug;
obstruction of the bile ducts;
severe forms of renal failure.

Treatment of cholecystitis and pancreatitis: treatment with medications

Choleretic drugs are prescribed only by a doctor.
The range is quite extensive, all medications have different prices, principles of action and other distinctive characteristics. Allohol is a choleretic agent for pancreatitis. The composition includes bile and dry extract of medicinal plants. The medicine promotes the active production of bile and improves intestinal functionality. The approximate dose is 8 tablets per day. Not allowed during pregnancy and lactation.

Cholenzym includes substances of animal nature. It has a beneficial effect on the digestive process, relieves smooth muscle spasms, and improves appetite. The maximum dose per day is 6 capsules.

Natural choleretics for inflammation of the pancreas:

Hologon is characterized by the most gentle effect and is suitable for the treatment of almost all patients. The result of use is revealed after twenty minutes.
Decholine is a choleretic agent, administered intravenously. It is acceptable to use for the treatment of many gastrointestinal diseases, including chronic pancreatitis and parapancreatitis.
Lyobil is available in tablet form and consists of natural bile. A special advantage of the drug is its ability to withstand the acidic environment of the stomach, so the capsules dissolve only in the intestines.

All drugs in the form of injections are used only in hospital settings. For home use are prohibited.

Synthetic choleretic medications:

Nicodin improves the excretion of bile, prevents congestion, and has an antibacterial effect. If you combine it with anti-inflammatory tablets, the inflammation will stop in a couple of days. Take four tablets per day. Sometimes the dose increases to 8 pieces;
Osalmide enhances the production of bile, eliminates muscle spasms in the abdominal cavity, reduces channel tension, reduces cholesterol levels, and normalizes the composition of bile.

Cyclalon is a choleretic and anti-inflammatory agent. Taken for a long time in courses of 4 weeks. Hymecromone is often prescribed, which works by changing the pressure ratio, which leads to increased production of water and electrolytes in the bile.

With pancreatitis, the condition of all surrounding organs is important. The work of the stomach and gallbladder is especially affected. High fat content in food can worsen the condition. Accordingly, when treating inflammation, it is important to choose a drug to facilitate the digestion process. In addition to enzymes, specialists often prescribe a choleretic agent.

During the treatment of pancreatitis, choleretic drugs are prescribed, which facilitates the process of food processing

These choleretic drugs have a stimulating effect and increase bile production. They can be divided into several groups based on their composition. The first group includes true choleretics. They stimulate the production of bile acids. They can be synthetic, containing bile and plant-based.

The second group is choleretic drugs that enhance production due to the water component. This includes mineral waters and other hydrocholeretics. It is noteworthy that valerian solution can be included in this same group due to its ability to stimulate bile production.

The drugs in these groups differ in their mechanism of action. True choleretic agents increase secretion production and increase the concentration of cholates. Water ones only irritate the mucous membrane of the small intestine, which causes increased production of bile.

After using choleretic drugs, the urge to vomit disappears

As a result of the use of choleretics, the following effects are observed:

improvement of the digestion process;
increased intestinal motility;
improved absorption of vitamins;
elimination of itching caused by stagnation of bile;
reduction of pain and elimination of nausea.

A choleretic agent is used for pancreatitis only outside the acute stage as prescribed by a doctor, taking into account the diet used.

Types of choleretics

To eliminate heaviness after eating and improve the digestion of fats in pancreatitis, the following choleretic drugs can be prescribed:

Allohol. Contains bile and dry plant extracts. Enhances bile production and improves intestinal function. Take up to 8 tablets per day.

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These drugs improve digestion and intestinal function

Cholenzym contains components of animal origin. It has a positive effect on digestion, relieves spasms and increases appetite. The maximum dosage is up to 6 tablets per day.
Hologon has the mildest effect and is suitable for most patients. The effect of taking a choleretic drug is observed within twenty minutes.
Decholin is a drug for intravenous administration. Can be used for a large number of pathologies, including pancreatitis.
Lyobil are tablets containing natural bile. An important advantage is that this remedy is able to resist gastric acid and dissolves only in the intestines.

All injectable drugs for pancreatitis are used only in a hospital setting under the close attention of doctors.

Choleretic drugs of this group are used not only for pancreatitis. They will be especially effective for cholecystitis, cholangitis, gastritis and intestinal inflammation. They can also be used for dietary disorders.

If there is inflammation in the intestines, choleretics also help

Preparations with synthetic components are included in a separate group. Nikodin is prescribed quite often. This remedy not only improves the excretion of bile, but also has a bactericidal effect. In combination with anti-inflammatory drugs, it allows you to quickly achieve a pronounced effect. The drug is taken up to 4 tablets per day. In extreme cases, the dosage can be increased to eight tablets.

The next synthetic drug is Osalmid. The active components of the product have the following effects:

secretion of bile;
elimination of spasm;
decreased duct tone;
reducing the amount of cholesterol;
normalization of bile composition.

With the help of synthetic choleretics, the spasms that occur with pancreatitis can be eliminated

Cyclovalon is a choleretic agent with anti-inflammatory properties. The medicine is taken for a long time - in courses of 4 weeks. Also synthetic drugs include Gimecromone. It acts by changing the pressure ratio, which causes an increased secretion of water and electrolytes into the bile. The medicine quickly relieves heaviness and nausea, but if the dosage is exceeded, it can cause diarrhea and stomach irritation.

Phenipentol has similar properties. It improves bile secretion and also activates the action of lipase in pancreatic juice. This medicine is not used for acute inflammatory processes of the digestive system.

Especially often at home, choleretic drugs are used, which contain only herbal ingredients. They have a minimum of contraindications and are easily tolerated. For pancreatitis, they will be appropriate beyond the acute stage in order to improve digestion in case of errors in the diet.

Herbal choleretic agents are used as prescribed by a doctor after ruling out the presence of gallstones. Use in accordance with the instructions, without exceeding the dosage.

In addition to medications, you can use traditional medicine that has a choleretic effect.

This group includes:

Barberry, used in the form of an alcohol tincture in the amount of 20 drops per dose. Improves bile production and relieves spasms.
Berberine bisulfate has a mild effect and can be used even in the presence of small stones in the gall bladder.
Immortelle. Decoctions of dried herbs improve intestinal motility, relieve tension in the gland and help eliminate bacteria.
Flamin has the same properties as dry immortelle herb. Convenient to use and easily tolerated due to its natural composition.
Tansy is most often used in the form of a tincture. Improves bile production and makes it less viscous.
Holosas is an aqueous extract used to normalize digestion and relieve spasm of the bile ducts. It has a positive effect on the condition of the pancreas due to its high content of vitamins.

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Cholekinetics

Also, for pancreatitis, other choleretic drugs can be used. They stimulate bile excretion and are called cholekinetics.

Duspatalin and Metacin are used among cholekinetics for pancreatitis.

Conventionally, all funds included in this group can be divided into two types:

increasing the tone of the gallbladder and at the same time relieving spasm from the ducts;
drugs whose action is aimed only at relieving spasm from the ducts.

The first include magnesium sulfate, Choleritin and Xylitol. The second group includes Duspatalin, Olimethine and Metacin. Such drugs are especially often used for digestive disorders, as well as when planning diagnostics. They simultaneously relax the sphincter and increase the tone of the gallbladder. At the same time, it is important to note that they are not used for acute inflammation of the liver, dystrophic phenomena and jaundice.

All choleretic drugs have an irritating effect, so they should be taken only in the absence of an acute process. Proper use of such remedies will speed up the process of breaking down fats and carbohydrates and thereby relieve the burden on the digestive organs. In addition, by dissolving in the intestines, they improve the absorption of fat-soluble vitamins, which has a positive effect on the general condition of the body and the immune system.

peptic.ru

Any disease affecting internal organs can cause many problems, but the combination of inflammation of the pancreas and gallbladder creates the most serious problems. Treatment of cholecystitis and pancreatitis with medications must necessarily be complemented by a strict diet, the purpose of which is to reduce the load and improve the functioning of the most important organs.

Pharmacological characteristics of Hofitol

The active substance is an extract from field artichoke leaves. This plant has a beneficial effect on the gastrointestinal tract. Release forms: oral solution, tablets.

Hofitol tablets and solution

The medicinal properties are due to the presence of useful biologically active compounds:

B vitamins;
organic acids (glyceric, quinic, glycolic, caffeic);
inulin polysaccharide;
minerals and trace elements (calcium, phosphorus, iron);
cynarin glycoside.

The following effects are characteristic of Hofitol:

Stimulation of bile synthesis.
Dilation of the ducts involved in the excretion of digestive juices.
Protecting the liver from the effects of harmful factors (drinking alcohol, drugs, smoking, stress, unbalanced nutrition).
Increased diuresis (diuretic effect).
Reducing the concentration of cholesterol and urea in the blood.
Removal of toxic compounds from the body (metabolites of drugs, salts of heavy metals, breakdown products of alcohol, nitrates).
Normalization of metabolic processes in the body.

Each tablet contains 200 mg of dried herbal extract.

Approved for use by pregnant and nursing mothers as prescribed by a doctor. In obstetrics it is prescribed for the treatment of toxicosis in pregnant women.

In pediatrics it can be used from the age of six.

Possible side effects associated with the use of Hofitol:

dyspeptic disorders (nausea, diarrhea);
skin itching, rash and other allergy symptoms.

The medicine is taken before meals with a drink.

For children, the recommended dosage is 1-2 tablets per dose. There are 3 such receptions per day.

A single dose for adults is 2.5-5 ml of liquid extract or 2-3 tablets.

The therapeutic course lasts 2-3 weeks. On the recommendation of a doctor, the course of treatment can be repeated.

Ursodeoxycholic acid preparations

Trade names under which they are sold in pharmacies: Ursosan, Ursofalk, Ursodez.

Available in capsules. A liquid dosage form, a suspension, has been developed for children.

During a course of treatment the drug:

Protects mucous membranes during reflux disease.
Restores hepatocytes, cholangiocytes (bile cells).
Stimulates bile secretion.
Prevents the development of atherosclerosis.

Contraindications:

gallstones with a high concentration of calcium;
non-functioning gallbladder;
acute pathologies of the gastrointestinal tract, kidneys.

Has no age restrictions.

In pediatric practice, they focus on the child’s ability to swallow a capsule.

Take 3 times a day, the number of capsules depends on the age and body weight of the patient.

Treatment is long-term – from 6 months to several years.

Cholespasmolytics

Effective drugs for inflammation of the pancreas are cholespasmolytics. Choleretic drugs for pancreatitis are prescribed to reduce the tone of the bile ducts and reduce spastic phenomena. To relieve spasms and pain, you can take the following medications: Drotaverine, Papaverine, Maxigan, No-shpa, Spazmalgon.

Atropine is most often prescribed as part of complex therapy for pancreatitis. In the acute form of the disease, as a rule, an injection solution is used, injecting it subcutaneously. For chronic pancreatitis, the drug is prescribed in courses.

Traditional medicine recipes are no less effective for treating the pancreas. Choleretic collection for pancreatitis is used not only for the main treatment, but also for the prevention of the disease. To prepare teas, decoctions and infusions, traditional healers recommend using mint, St. John's wort, and chamomile.

Allohol

Combined domestic medicine in tablets. It works through a combination of activated carbon, bile, nettle and garlic extracts.

For pancreatitis it is useful because:

Stimulates the motor activity of smooth muscle structures of digestion.
Activates the secretory function of the digestive glands.
Eliminates dyspeptic symptoms (increased gas formation, flatulence).

Indications for use:

Diseases of the biliary tract, liver (hepatitis, cholangitis, cholecystitis, pancreatitis).
Chronic constipation caused by intestinal atony.

Not used for:

Acute diseases or stages of exacerbation of chronic diseases of the digestive tract (hepatitis, pancreatitis, peptic ulcer, etc.).
Liver dystrophy.

Take after meals with water.

In the first month, take 1-2 tablets 3-4 times a day. After that, take 1 tablet 2-3 times a day for 1-2 months. Possible repeat course after 3 months

For what purpose are choleretic drugs prescribed for pancreatitis?

The pancreas is an important organ of the digestive system, which has a mixed function: internal and external. Internal secretion involves the production of hormones (insulin and glucagon) that regulate the metabolism of carbohydrates and lipids. The exocrine function of this organ is responsible for the production of pancreatic juice, which, in addition to water and various microelements, includes many enzymes and enzymes. They serve to break down proteins, fats and carbohydrates into components that are absorbed by the walls of the gastrointestinal tract.

In the normal state, these enzymes in the gland are in a passive state. Only when they enter the digestive tract are they activated to digest food. But under the influence of certain factors (alcohol, stress, drug intoxication, diseases of nearby organs), they can be activated, which causes inflammatory processes.

The most common cause of pancreatitis is various disorders associated with the outflow of bile, including gallstone pathology.

To combat these manifestations, choleretic drugs are prescribed, which help improve the processes of assimilation and digestion of food. Medicines also help reduce the secretory load on the pancreas. In addition, they help eliminate swelling and bile stagnation.

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Depending on the main pharmacological activity, all choleretic drugs are usually divided into 3 large groups: choleretics, cholekinetics and cholespasmolytics.

Tykveol

The drug is made in Russia. Can be used in oil or capsule form.

Pharmacological effects from the use of Tykveol:

protects organ cells;
eliminates inflammation;
slows down the pathological development of connective tissue in internal organs;
stimulates bile production;
improves the condition of the gallbladder;
normalizes the chemical composition of bile;
reduces the content of harmful fractions of cholesterol;
reduces the risk of developing bile stagnation and spasms of the bile ducts;
activates microcirculation and tissue regeneration in case of trophic disorders.

Take 4 capsules with meals or 1 teaspoon of oil 30 minutes before meals 4 times a day. The duration of the course is at least a month.

Attention! Shake the bottle of oil before use.

Not used to treat patients under 12 years of age.

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Choleretic fees

Choleretic herbs are widely used for pancreatitis. Alternative medicine offers many recipes based on herbal ingredients to eliminate the inflammatory process in the pancreas. The most popular are the following:

Collection No. 1. To prepare a healing drink, you need to take 2 parts of mint and coriander, 3 parts of trefoil and 4 parts of immortelle. Pour 2 tablespoons of thoroughly mixed ingredients into ½ liter of boiled water and leave. The decoction is consumed fresh, so it should be prepared every day.
Collection No. 2. To make a healing remedy for pancreatitis, you need to prepare the same components as in the first collection, but only replace the immortelle with caraway inflorescences, and the trefoil with yarrow. The cooking scheme remains the same.
Collection No. 3. You can relieve inflammation from the pancreas with the help of herbs from the first and second collections, to which you should add chamomile and marigold. The cooking method does not change.

Gepabene

Extracts of the fruits of milk thistle and the herb fumitory are used as active substances. Produced by the German company Merckle in the form of capsules for oral administration.

The drug normalizes the amount of secreted bile, relieves spasm of the ducts, and facilitates the flow of bile into the intestines. Restores cells (hepatocytes), protects them from damaging substances.

Not used to treat children and adolescents under 18 years of age.

Used with meals. Per dose: 1 capsule, 3 times a day.

Note! The integrity of the capsule must not be damaged; it must be taken whole without chewing.

For pain at night, take an additional 1 capsule before bed. The maximum daily dose is 6 capsules. The duration of therapy is determined by the attending physician individually.

Types of choleretics

To eliminate heaviness after eating and improve the digestion of fats in pancreatitis, the following choleretic drugs can be prescribed:

Allohol. Contains bile and dry plant extracts. Enhances bile production and improves intestinal function. Take up to 8 tablets per day.

These drugs improve digestion and intestinal function

Cholenzym contains components of animal origin. It has a positive effect on digestion, relieves spasms and increases appetite. The maximum dosage is up to 6 tablets per day.
Hologon has the mildest effect and is suitable for most patients. The effect of taking a choleretic drug is observed within twenty minutes.
Decholin is a drug for intravenous administration. Can be used for a large number of pathologies, including pancreatitis.
Lyobil are tablets containing natural bile. An important advantage is that this remedy is able to resist gastric acid and dissolves only in the intestines.

All injectable drugs for pancreatitis are used only in a hospital setting under the close attention of doctors.

If there is inflammation in the intestines, choleretics also help

Odeston

Tablet preparation containing hymecromone.

Therapeutic effect:

Increases bile synthesis.
Eliminates spasm of the ducts and sphincter of Oddi, without affecting blood pressure or suppressing the natural motility of the gastrointestinal tract.
Reduces stagnation processes.
Prevents the development of cholelithiasis.

Recommended for recovery after operations on the gallbladder and bile ducts.

Contraindications for use, in addition to general ones:

children and adolescents up to 18 years of age;
hemophilia;
pregnancy and breastfeeding.

Take the tablets 30 minutes before meals with water. Recommended dose for adults – 1-2 pcs. The number of doses per day is 3 times, for 2 weeks. The maximum daily dose is 6 tablets.

Important points when taking choleretic drugs

For diseases of the digestive system, taking medications is associated with meal times. So, taking choleretic drugs is subject to important rules:

all drugs in this group are taken before meals;
divide the daily dose of the drug by the frequency of meals;
Take the medicine with enough drinking water;
Be sure to eat within 30 minutes after taking the medicine;
the duration of therapy and the dose of the drug must be agreed with the attending physician;
the standard course of treatment lasts from 4 to 8 weeks;
preventive courses are carried out in spring and autumn, during seasonal exacerbations.

If alarming symptoms appear, you should immediately consult a doctor for differential diagnosis. Manifestations of Crohn's disease, cholelithiasis, gastritis, and ulcerative lesions of the gastrointestinal tract have similar symptoms.