Is De-Nol effective for GERD and heartburn?

De Nol for reflux gastritis

De-Nol is a bismuth-based drug that is prescribed to patients with GERD, esophageal erosions, and esophagitis.
The drug affects the underlying factors that provoke heartburn. During therapy, the mucous membrane becomes more resistant to the effects of bile and hydrochloric acid. De-Nol for reflux is used in complex therapy together with other groups of drugs.

The doctor will be able to answer the question of how long to take the pills after an in-person examination.

Composition of the drug and the effect of active substances on the esophageal mucosa

De-Nol is an antiulcer drug based on complex bismuth salts. Stimulates the natural synthesis of mucus, which protects the mucous membrane from damage. Normalizes acidity levels in the gastrointestinal tract. The drug is active against Helicobacter pylori, enhances the effectiveness of antibiotic therapy and antimicrobial agents.

The active substance exhibits the following pharmacological properties:

• enveloping,
• antimicrobial,
• astringents,
• anti-inflammatory.

Bismuth quickly dissolves under the influence of the acidic environment of the gastrointestinal tract, compounds are formed that do not dissolve and combine with protein tissues. The medicine forms a protective film on the surface of the mucous membrane. Prevents the aggressive effects of gastric juice components.

Bismuth does not disrupt intestinal motility and digestive processes, since the film is formed only on damaged areas of the mucosa.

Does De-Nol help with heartburn?

Heartburn is accompanied by the reflux of gastric juice into the esophagus. De-Nol is not a first aid or symptomatic therapy. The drug will exhibit a proper therapeutic effect with long-term, systematic use. Single use of tablets is not recommended and will not have the expected therapeutic effect.

De-Nol affects the underlying factor causing the symptom. Helps cope with heartburn caused by:

• chronic gastritis, which is accompanied by high acidity,
• ulcerative lesions of the stomach and duodenum,
• reflux esophagitis.

The medicine is used for 1-2 months. Longer use is not recommended: excessive accumulation of bismuth provokes unwanted reactions in the body. The drug is taken 2-4 tablets per day, before meals. The gastroenterologist determines the exact dose and frequency of administration individually. The maximum daily dose is 480 mg.

Regimens and doses of De-Nol for the treatment of GERD

Therapy of gastroesophageal reflux disease requires an integrated approach involving medications and diet therapy.

During rest, the patient is recommended to be in an elevated position: the head end of the bed is at a distance of up to 20 cm, high pillows. Spicy, fatty, heavy, fried foods are excluded from the diet.

It is also recommended to avoid coffee, chocolate, soda, citrus fruits, garlic, and onions. Food is taken often, in small portions, and overeating is avoided. The last meal is 3.5-4.5 before bedtime.

Drug therapy involves the use of proton pump inhibitors based on omeprazole or lansoprazole, antacid drugs as a means of symptomatic therapy (Reni, Maalox). The tablets should be taken together. De-Nol can be used in several ways:

• 1 tablet up to 4 times a day: on an empty stomach, before each meal (half an hour before), and also before bedtime,
• two-time use: on an empty stomach before breakfast, in the evening before going to bed. The medicine is washed down with purified, plain water. Milk, juices, decoctions, compotes are not suitable for this purpose and are incompatible with De-Nol.

It is necessary to maintain an interval of at least 60-120 minutes between the use of bismuth and other groups of medications recommended by the doctor.

Bismuth is used as part of complex therapy, along with other groups of drugs prescribed by a gastroenterologist. The drug is not intended for self-medication; it is used after a comprehensive diagnosis.

Rules for the treatment of esophageal erosion with De-Nol

Modern gastroprotective drugs based on bismuth are used in the treatment of gastric dysfunction. De-Nol is also recommended for patients with ulcerative and erosive lesions of the walls of the gastrointestinal tract.

At the first symptoms of a disorder, you must consult a doctor and undergo a comprehensive examination. The specialist selects a treatment protocol.

Bismuth preparations are used according to several schemes: taking tablets twice or four times a day. The maximum daily dosage is up to 480 mg.

The duration of taking the tablets is up to 2 months. If during this time the patient does not feel relief, it is necessary to consult a doctor again and reconsider the treatment regimen.

Preparations for complex treatment of esophagitis with De-Nol

The initial stage of esophagitis is eliminated with the help of diet therapy. In other cases, patients are recommended to take:

• De-Nola for esophagitis,
• antisecretory drugs,
• proton pump inhibitors (Omeprazole, Pantoprazole, Lansoprazole),
• prokinetics (Motelac, Motilium, Cerucal). The medicine will speed up the movement of food through the gastrointestinal tract and speed up intestinal evacuation. Selective drugs of the new generation act more gently and safely,
• antacids (Maalox, Gastal, Almagel) - means of symptomatic relief that act for a short time. With prolonged use, they provoke reverse emissions, deterioration of well-being, and increased gas formation.

Proton pump inhibitors (PPIs) are the basic treatment for esophagitis. Such medications normalize acidity levels and maintain therapeutic effectiveness from 30 days to 12 months after completion of the course of treatment. The selection of a suitable active substance and dosage is carried out after obtaining the results of pH measurements.

The dosage of medications and the course of therapy depend on the degree of development of the inflammatory process, the clinical picture, concomitant diseases, and the individual characteristics of the patient’s body. An interval is maintained between taking bismuth and other medications. Patients with gastrointestinal problems should be under constant medical supervision.

Source: https://geraklionmed.ru/de-nol-pri-reflyuks-gastrite/

De-Nol for heartburn: does it help with GERD, reflux, esophagitis

22.02.2019

De-Nol is a bismuth-based drug that is prescribed to patients with GERD, esophageal erosions, and esophagitis. The drug affects the underlying factors that provoke heartburn.

During therapy, the mucous membrane becomes more resistant to the effects of bile and hydrochloric acid. De-Nol for reflux is used in complex therapy together with other groups of drugs.

The doctor will be able to answer the question of how long to take the pills after an in-person examination.

Special conditions of admission

The first thing to consider is that you need to take De-nol only with your doctor's permission. In addition, it is important to follow a diet during treatment. It consists of completely eliminating dairy products and some fruits, including fruit juices. This is explained by the fact that when simultaneously entering the stomach, the effectiveness of the active components of the drug decreases.

In addition, it is not recommended to use this drug for more than eight weeks. It is strictly forbidden to exceed the dosage, especially in cases where reflux in children is eliminated.

Only a doctor should prescribe treatment with De-nol

Do not be afraid of such a symptom as a change in the color of stool. This is due to the high content of bismuth sulfite in it. This does not cause any complications and only indicates the complete removal of active components from the body.

De-Nol for gastritis: instructions for use, reviews from doctors and patients, analogues

De-nol is gastroprotector No. 1 on the recommendation of therapists and gastroenterologists. Gastritis is one of the reasons for prescribing a drug.

Let's figure out in what cases De-nol is prescribed for gastritis, how to take it correctly in order to achieve a positive result without harming your health. How do patients respond to him? Does it have analogues and what is their difference?

Composition and release form

De-nol tablets for internal use, coated, containing bismuth tripotassium dicitrate as the active substance.

The presence of a slight characteristic odor of ammonia is allowed.

pharmachologic effect

The drug has therapeutic effects:

• compacts the top layer of areas with erosion;
• stimulates growth factor in pathologically altered cells;
• activates regeneration processes;
• protects the walls of the digestive tract from the pathological effects of an aggressive environment (enzymes, hydrochloric acid and bile acids);
• reduces the inflammatory reaction in the damaged area;
• kills Helicobacter pylori bacteria, which contribute to the occurrence of peptic ulcers;
• reduces stomach pain;
• eliminates dyspeptic symptoms (nausea, belching, heartburn);
• reduces the frequency of relapses and exacerbations.

Mechanism of therapeutic effect

The tablet reacts with gastric juice - precipitation of insoluble bismuth salts occurs, which in turn react with proteins to form surface foamy compounds.

A protective film in the form of a white coating forms on the ulcerated areas. It persists for several hours. This process prevents the traumatic effects of aggressive biologically active substances (bile salts, enzymes, hydrochloric acid) on the mucous membrane of the stomach and intestines.

The enzymatic activity of digestive juices also decreases.

The medicine stimulates the synthesis of prostaglandins, as a result of which the secretion of mucin (mucous substance) and other compounds increases, and the properties of gastric secretions improve. In the area of ​​erosive damage, regenerative processes are stimulated.

Coagulation of protein molecules, which accompanies the transformation of the drug substance, destroys pathogenic microorganisms of the Helicobacter pylori strain.

Indications

It is advisable to use De-nol for the treatment of pathologies of the digestive organs, including those caused by Helicobacter pylori:

• exacerbation of duodenitis and gastroduodenitis ;
• peptic ulcer of the duodenum and stomach;
• reflux esophagitis;
• irritable bowel syndrome;
• gastritis ( atrophic , chronic , erosive );
• dyspeptic symptoms (heartburn, nausea, belching, epigastric pain, constipation, diarrhea) in the absence of diseases of the internal organs).

It is used for intensive therapy (in the acute phase) and for preventive courses.

Contraindications

The drug is not recommended for use if:

• serious kidney disease;
• pregnancy;
• lactation (breastfeeding);
• individual hypersensitivity to the ingredients of the tablets.

Rules of use

For half an hour before and after taking the pill, you should avoid:

• fruit;
• drinks (milk, fruit juices);
• solid food.

When taking these products simultaneously, the effectiveness of De-Nol decreases, because The substances contained in the products enter into a chemical interaction with bismuth.

Take the tablet with drinking water. During treatment, it is necessary to follow the daily and single doses prescribed in the instructions.

The use of large doses of gastroprotector provokes the development of side effects. The course of treatment should not last more than 2 months. After completing the course of De-nol tablets, it is not recommended to take other bismuth-containing medications for 2 months.

How to take De-nol for acute gastritis

Therapeutic dosage depends on:

• patient's age;
• diagnosis;
• body weight (for children's practice).

Traditionally, for acute gastritis and peptic ulcers, the following doses are prescribed:

It is recommended to take one dose at night. For convenience, it is allowed to divide the daily dose into 2 doses (in the morning and evening), 30 minutes before meals.

Side effects

When using De-nol, various side effects may occur.

Most often noted:

• allergic reactions (skin itching, urticaria);
• darkening of the tongue;
• dyspeptic symptoms;
• staining stool black.

In rare cases, anaphylactic shock and encephalopathy develop (when taking large doses of bismuth for a long time, it accumulates in the cells of the brain and spinal cord).

After stopping the use of the tablets, the symptoms disappear. Discontinuation of the medication is not required (with the exception of an acute allergic reaction in the form of anaphylaxis, when emergency medical care and discontinuation of the source of the allergen are required).

Overdose

Overdose occurs with prolonged use of excessive doses or impaired excretory function of the kidneys.

In case of bismuth poisoning the following are observed:

• dyspeptic symptoms;
• stomatitis (inflammation of the oral mucosa);
• specific blue lines on the surface of the gums;
• skin rash;
• pathological processes in the kidneys.

Symptoms disappear after stopping treatment.

Gastric lavage is recommended, followed by the administration of sorbents (Polysorb, Polyphepan, Enterosgel, white carbon, activated carbon, Filtrum-STI) and laxatives (Magnesium sulfate salt). To eliminate discomfort, symptomatic medications (antispasmodics) are prescribed.

When there is a high level of bismuth in the blood plasma against the background of renal pathology, complexing acids are used. They enter into a chemical reaction with bismuth and precipitate it in the form of salts. In case of serious problems with the kidneys, hemodialysis is performed.

Interaction with other drugs

Combination therapy directed against the pathogen Helicobacter pylori is recommended, using:

• Metronidazole ( Trichopol );
• Amoxicillin ( Amoxiclav , Augmentin , Amosin , Flemoxin );
• Clarithromycin ( Klacid ).

In this case, there is a mutual increase in antimicrobial activity. Bismuth interferes with the absorption of tetracycline and weakens its antibacterial effect.

The use of De-nol for gastritis together with proton pump inhibitors ( Omez , Nolpaza , Omeprazole , Nexium , etc.) enhances the mutual gastroprotective effect.

Drugs containing bismuth or its combinations ( Vicair , Vikalin ) increase the risk of overdose.

Taking antacids (
Almagel , Gastal , Rennie, Maalox , etc.) is possible 30 minutes before or after using De-nol.
To eliminate pain, it is allowed to use antispasmodics ( No-shpu, Duspatalin , Dicetel , Buscopan ).

De-nol protects the gastrointestinal mucosa from the irritating effects of non-steroidal anti-inflammatory drugs (NSAIDs).

Interaction with alcohol

Alcohol enhances the toxic effects of the drug.

It should be borne in mind that alcohol can be contained not only in strong alcoholic drinks, but also in some herbal medicines (tinctures, extracts, balms).

Analogs

On average in Moscow, the cost of a De-nol package of 56 tablets is 520 rubles, 112 tablets – 970 rubles. The tablets are expensive, so patients are interested in substitutes at an affordable price. Another reason that requires replacing the original medicine is intolerance to the components of the drug.

Analogs of De-nol can be divided into 2 groups:

Preparations identical in active substance:

Other gastroprotectors

Reviews from doctors and patients

Reviews from people who took De-nol for gastritis confirmed its effectiveness.

They listed the following advantages of the drug:

• rapid relief of symptoms accompanying stomach disease (heartburn, belching, pain in the epigastrium);
• long-term therapeutic effect;
• Possibility of use by drivers and persons whose professional activities require concentration;
• reliable manufacturer (Astellas, Netherlands);
• suitable for treating children;
• sold everywhere, without a doctor's prescription;
• well tolerated.

The disadvantages are considered:

• high cost;
• requires the use of other medications;
• lack of a children's dosage form; tablets are inconvenient to give to young patients.

Reviews from doctors who recommended De-nol for gastritis are consistent with the opinions of patients.

Additionally, experts note the fact that after learning its cost, patients with low incomes refuse to buy it. Because of this, the effectiveness of treatment decreases, and prescriptions have to be adjusted.

Serious side effects and poisonings occurred extremely rarely.

The positive point is that there are a minimum of contraindications, which is why the drug can be recommended to most people suffering from diseases of the digestive system.

Conclusion

De-nol is an effective remedy for the treatment of pathologies of the intestines and stomach. Its effectiveness has been confirmed by decades of practical gastroenterology. When treating gastritis in the acute stage, it is prescribed in combination with other drugs that restore the normal functioning of the gastrointestinal tract.

Source: https://GastrituNet.online/bolezni-zheludka/gastrit/lechenie-g/preparaty/de-nol-pri-gastrite.html

De-nol: instructions for use for gastritis - how to take it correctly

Diseases of the digestive tract often bother adults. Inflammatory processes of the stomach occupy leading positions in the structure of organ pathology. The specialist’s task is timely treatment and prevention of exacerbations. The course of therapy includes the use of bismuth preparations.

De-Nol for gastritis is included in the eradication scheme for Helicobacter pylori, which in most cases is the cause of inflammation. It is important to follow the instructions and take the medicine correctly.

Use of De-nol for gastritis

Bismuth subcitrate, entering the lumen of the gastrointestinal tract, almost does not penetrate into the systemic circulation. The active substance forms a special film on the surface.

A small part of the drug is eliminated through the kidneys, the rest is excreted in the feces.

The application regimen specified in the De-nol instructions allows you to achieve the required concentration of the main component to achieve the following results:

Important! The method of application and duration of taking the drug depend on the severity of the process, the type of pathology and the presence of concomitant diseases.

When using the drug, there is a risk of side effects. Undesirable clinical consequences of administration are represented by the following symptoms:

• dyspeptic symptoms - nausea, vomiting, unstable stools, sometimes stomach pain;
• allergic manifestations - rash, itching, in severe cases - anaphylactic shock;
• a change in the color of stool, even black, due to the formation of bismuth sulfide.

Bismuth subcitrate is contraindicated in case of renal failure and a history of allergic reactions to the components of the drug. The drug is not recommended for pregnant and lactating women, given the lack of reliable information on use in this category of patients.

How to take De-nol correctly for gastritis

The drug is prescribed for various forms of inflammation of the stomach during exacerbation and for prevention according to the scheme presented in the table.

Attention! After completing the course, you should take a break of up to 2 months. This is due to the possible accumulation of bismuth and the risk of encephalopathy.

How to drink De-nol for gastritis: before or after meals

To get a positive result, follow the recommendations for using the medicine. It is necessary to drink De-nol correctly for gastritis with high acidity and low acidity, as well as other disorders of the gastrointestinal tract.

Take the tablets half an hour before meals at regular intervals. The last dose is before bedtime. Do not consume the substance simultaneously with milk or juice, only with a small amount of water.

Any liquid other than water interferes with the therapeutic effect of the drug.

Carefully! During therapy, the use of other products containing bismuth is not allowed.

How much to drink De-nol for gastritis

The treatment regimen and course duration are prescribed by a gastroenterologist. In each specific case, the specialist determines individually how much De-nol to take for gastritis or other pathologies.

The duration of the course ranges from 4 to 8 weeks.

To eliminate Helicobacter pylori infection, bismuth subcitrate should be taken for 7-14 days, and then continued after eradication for up to 6 weeks inclusive as maintenance therapy.

For children

The drug is prescribed not only to adults. Doctors successfully use De-nol for children with gastritis and functional disorders of the digestive system. The treatment regimen has features in different age groups.

De-nol for the prevention of gastritis

Prevention of the disease is a prerequisite for a positive result of therapy. Gastroenterologists recommend taking De-nol for the prevention of gastritis as an alternative if drugs that normalize the secretion of hydrochloric acid are insufficiently effective. The drug can also be combined with H2-histamine blockers and proton pump inhibitors.

https://www.youtube.com/watch?v=Wc2q3S36WWU

Bismuth subcitrate is prescribed as planned 2 times a year in the fall and spring, taking into account the high risk of relapse during the off-season. In the absence of symptoms of the disease, the duration of therapy ranges from 10 to 14 days.

If there is an exacerbation of pathology, additional diagnostics are carried out. Identification of Helicobacter pylori is an indication for an eradication course, which includes a combination of De-nol with antibiotics and medications that regulate gastric acidity.

After this, the maintenance preventive course is continued for up to 6-8 weeks.

Treatment of gastritis with De-nol with other drugs

Therapy for gastritis involves the use of several medications. The mechanism of action of bismuth subcitrate is determined by the reaction of the active substance and hydrochloric acid with the formation of a protective film. Therefore, the peculiarities of drug interactions should be taken into account.

1. Between taking antacids, such as Phosphalugel, Almagel, and De-nol, a break of at least 30 minutes should be observed.
2. A time interval is necessary when carrying out eradication therapy with antibiotics. This is due to a decrease in the concentration of tetracycline in the blood during treatment with bismuth.
3. Proton pump inhibitors - Omeprazole, Omez, Ultop - do not interact with the substance. Therefore, medications can be taken at the same time.
4. Bifiform is drunk regardless of food. The bacterial drug improves the effectiveness of eradication therapy. Combination with De-nol is allowed, but it is not used together with antibiotics; you need to take the drug after completing the course of antibacterial therapy.
5. There is no interaction of bismuth with gastrointestinal motility regulators - Motilium, Trimedat. You can take De-nol at the same time as this group of drugs.

Reviews from doctors and people who received them

Bismuth preparations have been used for many years to eliminate pathological conditions of the gastrointestinal tract. Thanks to its active properties, the medicine has established itself as an effective medicine.

When treated with De-nol, reviews from people who have taken it for gastritis are mostly positive. Patients say that unpleasant symptoms go away within a few days after starting therapy.

Most adults note a decrease in the number of relapses of gastritis when taking the drug systematically.

Experts observe excellent tolerability of bismuth subcitrate. Reviews from doctors indicate a low likelihood of adverse reactions and complications. This allows De-nol to be used in patients of different age groups.

This is of great importance in the treatment of gastritis and other forms of pathology of the digestive system in children, given the limited use of alternative remedies.

Several tablet release options allow you to prescribe a trial, economically affordable course of therapy.

An integrated approach to the treatment of gastritis with the inclusion of the drug De-nol guarantees high-quality and quick treatment results.

Recommended materials:

How to take Omez for gastritis

Symptoms of gastritis and stomach ulcers

Stomach erosion: symptoms and treatment, photo

Symptoms of gastritis of the stomach in adults

Treatment of gastritis with folk remedies: the most effective recipes according to reader reviews

Source: https://stomach-diet.ru/de-nol-pri-gastrite/

Contraindications and overdose

In most cases, De-nol is well tolerated by patients and even children and does not cause any life-threatening abnormalities. At the same time, when treating reflux esophagitis, it is important to take into account some contraindications:

• pregnancy;
• severe renal impairment;
• lactation period.

During long-term use of the drug, abnormalities such as constipation, nausea and vomiting may occur. Changes in the skin in the form of itching or rashes are also possible.

Such conditions do not require treatment adjustments or the use of additional funds. They go away on their own after discontinuation of the drug and are not dangerous to the human condition.

In rare cases, there is an accumulation of bismuth in the body. As a rule, the nervous system is affected. This leads to the formation of a pathology such as encephalopathy. This is accompanied by sleep disturbances, decreased sensitivity of the muscles of the back of the head, and impaired concentration and memory. This deviation does not require treatment. Immediately after stopping treatment, the symptoms of encephalopathy gradually disappear. In most cases, 10-20 days are enough for recovery, but signs of central nervous system damage may persist for up to 55 days.

The toxicity of bismuth is explained as follows: it is a heavy metal that is completely insoluble in water. Bismuth salts are the most dangerous, but they are formed in minimal quantities. With long-term use of the drug De-nol, symptoms of toxic effects such as the formation of a film located along the edge of the gums may appear. This contributes to the development of inflammation, swelling and hyperemia.

Treatment of reflux esophagitis with De-nol

With reflux esophagitis, irritation of the mucous membrane of the stomach and esophagus is especially common. In this regard, there is a need to use drugs with enveloping properties.

In addition, activity against Helicobacter would also be appropriate, since it is this microorganism that often becomes the cause of pathology. In such a situation, doctors most often prescribe De-nol.

But at the same time, it is important to understand how the drug works for this pathology and what features of its use exist.

Treatment of reflux esophagitis is carried out using De-nol

general description

De-nol refers to antiseptic drugs with enveloping properties. Used for ulcerative lesions of the gastrointestinal tract. The medicine is produced in the form of tablets of a special shape with concave surfaces on both sides. As a rule, the tablet is white, and the shell is colored milky or cream. No odor is noted, but a slight ammonia odor is acceptable.

The active ingredient is bismuth. It is contained in one tablet in the amount of 304.6 grams. The remaining components are secondary and do not play an important role. These include starch, magnesium stearate and povidone. De-nol is available in blisters of 8 tablets.

Immediately after entering the gastrointestinal tract, the active component of the drug reacts with proteins. A film is formed to protect ulcers and ulcerative lesions from irritation.

In parallel, increased mucus production occurs, which also has a positive effect on the condition of the mucous membrane. And increased production of prostaglandin E has a protective effect against acids and salts. It is especially important to note the fact that during regular use, an accumulation of cells is observed in the affected area, improving regeneration processes.

In addition to De-nol, Sucralfate is used in treatment

De-nol is excreted almost unchanged. As a rule, most of it is found in the feces and only a minimal amount enters the bloodstream and is subsequently excreted by the kidneys. Accumulation and absorption of bismuth in the body does not occur. This allows you to treat reflux for a long time without worrying about negative consequences.

There are other drugs that act in exactly the same way. First of all, this is Ventrisol. The active substance here is the same as in De-nol. It is also possible to use Sucralfate.

They are also effective for ulcerative lesions and severe irritation of the mucous membrane due to reflux esophagitis. But in any case, before changing De-nol to another drug, it is important to see a doctor and confirm reflux esophagitis.

Only after this does treatment begin.

How to take the drug

In order to achieve maximum effect, you need to take the medicine correctly. If reflux is detected and the doctor recommends taking De-nol, it is important to find an annotation for it and determine all the features of use and contraindications. This is done for the following reason.

During a visit to a doctor, it is not always possible to identify all possible contraindications and individual characteristics that may affect the effectiveness of treatment.

De-nol is indicated for gastritis

Only in a quiet home environment can you carefully read all the points in the annotation and understand whether you can take this drug, whether you can provide the conditions to achieve the effect, and what possible symptoms of side effects may arise.

The main indications are the following conditions:

• an ulcer localized in the stomach;
• reflux in the acute stage;
• acute gastritis;
• acute gastroduodenitis;
• severe dyspepsia;
• diarrhea caused by intestinal irritation.

To achieve the effect, it is important to follow the dosage. De-nol is used both in the treatment of adults and to eliminate symptoms in children. Thus, adult patients and children over 13 years of age can take one tablet every six hours. It is recommended to take the drug before eating. In addition, adults are allowed to take two tablets at once before bed or early in the morning.

During treatment, the dosage of the drug should be observed

Children under 13 years of age are allowed to take no more than two tablets per day. But for kids 4-7 years old, no more than one unit.

If you need to eliminate reflux with the help of the drug, you need to take it for a long time for 40-60 days. It is especially important not to take medications containing bismuth at the same time.

If there are signs of Helicobacter, the course is supplemented with antibiotics that are effective against the microorganism.

Special conditions of admission

The first thing to consider is that you need to take De-nol only with your doctor's permission. In addition, it is important to follow a diet during treatment. It consists of completely eliminating dairy products and some fruits, including fruit juices. This is explained by the fact that when simultaneously entering the stomach, the effectiveness of the active components of the drug decreases.

In addition, it is not recommended to use this drug for more than eight weeks. It is strictly forbidden to exceed the dosage, especially in cases where reflux in children is eliminated.

Only a doctor should prescribe treatment with De-nol

Do not be afraid of such a symptom as a change in the color of stool. This is due to the high content of bismuth sulfite in it. This does not cause any complications and only indicates the complete removal of active components from the body.

Special conditions of admission

The first thing to consider is that you need to take De-nol only with your doctor's permission. In addition, it is important to follow a diet during treatment. It consists of completely eliminating dairy products and some fruits, including fruit juices. This is explained by the fact that when simultaneously entering the stomach, the effectiveness of the active components of the drug decreases.

In addition, it is not recommended to use this drug for more than eight weeks. It is strictly forbidden to exceed the dosage, especially in cases where reflux in children is eliminated.

Do not be afraid of such a symptom as a change in the color of stool. This is due to the high content of bismuth sulfite in it. This does not cause any complications and only indicates the complete removal of active components from the body.