Dosage forms and composition of the drug
The active ingredient is omeprazole.
The substance dissolves exclusively in the intestines. The required concentration is achieved after half an hour or an hour. There are several types of release forms of this drug:
- Enteric capsules;
- Powder for suspension;
- Solution in ampoules for injections.
Capsules can contain 10, 20, 40 milligrams of active substance and easily dissolve in the intestines.
One bottle of injection solution contains 40 milligrams of Omeprozole.
Properties and pharmacological action of Omez
This medicine is intended to suppress secretion in the stomach. Antiulcer effect. The degree of basal secretion decreases with any stimulus. Omez takes effect an hour after administration and can remain in the body for 24 hours.
Maximum effect after two hours. When the drug is finished, secretion activity will be restored after four days.
The drug contains Domperidone. The substance has an antiemetic effect and improves the rate of gastric emptying.
Pharmacological properties
The drug "Omeprazole" belongs to the category of proton pump inhibitors, which reduce the production of hydrochloric acid due to the suppression of H/K-ATPase of parietal gastric cells. This pharmacological drug is considered a prodrug that works in the acidic biological environment of the secretory tubules of the gastric mucosa.
The drug "Omeprazole" also has bactericidal properties against Helicobacter pylori. Eradication of this infectious agent with the simultaneous use of this medication with antibiotics allows you to quickly eliminate the symptoms of an ulcerative pathological process in the stomach, achieve a high degree of regeneration of the damaged mucous membrane and stable long-term remission. In addition, this medication reduces the likelihood of bleeding in the digestive tract.
Indications for use of the drug
This medicine is prescribed only by a specialist for gastrointestinal ailments.
Omez is prescribed after special examinations:
- Necessary tests;
- Diagnostics using equipment.
The medication is prescribed for the following diseases:
- Peptic ulcer, exacerbation of gastric and duodenal ulcers;
- Gastric ulcers due to severe stress;
- Erosive-ulcerative esophagitis;
- Peptic ulcers resulting from taking a course of non-steroidal drugs that have an anti-inflammatory effect (NSAIDs, NSAIDs);
- Zollinger-Ellison syndrome;
- Erosive and ulcerative gastrointestinal disorders. The disease occurs due to cirrhosis of the liver;
- Reflux esophagid.
The medication is used in some cases of pancreatitis.
Features of using Omez D
This medicine is prescribed by a gastroenterologist to be taken in combination. It contains: Omeprazole and Domperidone.
The medicine has the following indications:
- Dyspepsia. Can be taken when adding heartburn to the ailment;
- Erosive-ulcerative esophagitis.
Has the following actions:
- Able to minimize nausea and eliminate the gag reflex;
- The esophageal sphincter is activated in its tone;
- Makes bowel movements faster. Peristalsis increases;
- Digestion begins to work more efficiently.
It is worth starting use after the recommendation of a specialist.
Other diseases
The drug "Omez" has an effective therapeutic effect for the following ailments:
- for stomach and duodenal ulcers;
- for gastritis;
- for gastric tract defects;
- with inflammation of the pancreas.
As you know, peptic ulcers worsen in the off-season. If you include this remedy in complex therapy, then the medicine “Omez” will not only help get rid of heartburn, but will also speed up the healing of the ulcer and completely relieve any discomfort.
Contraindications of the drug
The instructions provide information about the following contraindications:
- Lactation period;
- Pregnancy;
- Childhood;
- Individual intolerance to the active ingredient;
- Obstruction of the stomach or intestines;
- Bleeding in the stomach or intestines;
- Perforation of the intestines, stomach;
- A brain tumor.
Hypersensitivity to the components of the drug is extremely rare.
Caution should be taken when taking Omez for those who have liver failure or kidney problems.
If there are any suspicious symptoms (sharp weight loss, regular vomiting with blood, etc.), including stomach ulcers, you should make sure that there is no malignant tumor.
For this reason, an endoscopic examination is prescribed before taking the drug. It is necessary to ensure that the symptoms are not hidden, thereby hiding the true diagnosis and delaying treatment.
The instructions do not prohibit the joint use of the drug and alcohol. Omez does not affect what is contained in the stomach.
Side effects
Despite the fact that the drug is usually well tolerated by patients, very rarely symptoms of side effects may occur, manifested as follows:
- nausea, vomiting, digestive disorders and pain in the abdominal area;
- rash, itching and other allergic manifestations;
- visual impairment;
- increased activity of alanine aminotransferase and aspartate aminotransferase (liver enzymes);
- feeling of dryness in the mouth.
If these manifestations develop or other discomfort occurs, it is recommended to interrupt Omez therapy and seek advice from a specialist.
Can children take it?
There are exceptional cases in which the doctor prescribes this drug for children, reducing the dosage by half. Still, you shouldn’t risk it, because the instructions state a contraindication for children under eighteen years of age.
It is better to replace Omez with a diet or similar analogues of the drug that are safer for the child (Almagel, Famotidine).
Omez dosage
The dosage and duration of use varies depending on the diagnosis made by the doctor:
- It is often necessary to administer the drug intravenously.
Zollinger-Ellison disease requires taking one tablet three times a day. In some cases there is a need to increase the dosage. - In case of exacerbation of duodenal ulcer, the medication should be taken one tablet per day. The duration of treatment is a month.
- In case of exacerbation of a gastric ulcer , as well as erosive and ulcerative digestive disorders resulting from taking non-steroidal drugs, a long course of treatment is required, about several months, more often two months.
Capsules must be taken twice a day. It is often necessary to administer the drug intravenously (forty ml per day).
Method of administration of the medicine and dose
Capsules are taken orally. You need to drink it with clean non-carbonated water (do not chew the tablet), half an hour before meals.
Instructions for use:
- During the period of exacerbation of the ulcer, as well as with reflux esophagitis, take 20 milligrams twice a day - morning and evening. Treatment should last up to three weeks, if necessary - five weeks.
- To treat Zollinger-Ellison disease, you need to take 60 milligrams of the medicine.
- Preventive measures against Mendelssohn's syndrome - 40 milligram capsules at least one hour before surgery.
- In order to prevent recurrence of gastric and intestinal ulcers, you should take 20 milligrams once a day.
- For liver failure - take 20 milligrams per day;
- For pancreatitis, 120 milligrams are prescribed. Three times a day. The course of treatment may vary. From a couple of weeks to a month;
- To get rid of Helicobacter - 40 milligrams twice a day; Duration two weeks;
- For gastritis with increased acidity levels , you need to take one tablet per day. It is recommended to take the tablet on an empty stomach. Continue treatment for two months.
If your doctor prescribes intravenous administration, you should take from 40 to 70 milligrams during the day.
In case of overdose, unpleasant, discomforting symptoms are possible. Visual impairment, dry mouth, headache, sleep disturbances.
How long to take Omez without interruption
In case of disturbances in the functioning of the gastrointestinal tract, a drug such as Omez is prescribed.
But the important question that interested people are wondering is how long can Omez be taken.
Omez or Omeprazole, as it is also called, refers to medications that help normalize the production of gastric juice.
Thanks to the relief of symptoms, a person feels much better.
Increased acidity leads to the appearance of erosions and ulcers on the walls of the stomach.
Normalizing the acidity level will serve as a preventive measure not only for ulcers, but also for cancer disorders in the body.
Restrictions
It is not advisable to take this medicine if you are allergic to any of the components of this drug. You should take medications only after consulting your doctor.
Experts recommend using Omez carefully if you have diseases of the cardiovascular system, as well as with an insufficient amount of magnesium in the blood and liver dysfunction.
How to use
There are two options for the release of such a drug as Omeprazole. For example, powder for intramuscular injection into the body and capsules with microgranules.
It acts very quickly and in 30 minutes can eliminate an attack of pain due to gastritis. Additionally, it helps get rid of nausea and normalizes acidity levels.
The ideal option would be its combination with Phosphalugel. This drug can protect the stomach walls from damage.
Additionally, Omeprazole fights the cause of stomach ulcers, that is, the Helicobacter pylori bacterium.
How long can Omeprazole be used without interruption?
Like any other medicine, Omez can harm the body if you self-medicate and do not follow the norm when taking pills.
It is also not advisable to take it for a long time. You should stop taking it on the same day when the symptoms stop.
In severe advanced stages, it is recommended to take the drug intravenously. To eliminate acute gastritis, it is necessary to use the medicine in capsules.
You need to drink them twice a day: before meals in the morning and in the evening before bed.
The course of treatment should be within 30 days; if the disease is not advanced, then it must be reduced.
Sometimes doctors recommend taking Omez in capsule form for prophylactic purposes in the presence of diseases of the digestive tract. In this case, you need to drink one capsule per day.
How long can you take Omeprazole?
To avoid the occurrence of adverse reactions, you can use the medicine for no longer than 60 days. Moreover, this must be done only under the supervision of a medical specialist.
He will select the necessary method of rehabilitation therapy for a specific disease.
Is it possible to take Omez on a regular basis?
It is not recommended to use Omeprazole on a regular basis. It is necessary to take a break for several months.
It is impossible to restore the body with the help of one drug; this requires complex treatment. Self-medication can negatively affect a person’s health.
Restrictions on the use of Omez
It is necessary to take Omez especially carefully if the patient’s age exceeds 50 years.
The problem is that with long-term use of the drug, improper distribution of calcium can occur.
This may pose a risk of bone depletion and bone fracture.
Do not take the medicine during pregnancy and lactation. It is also undesirable to use Omez for children under one year of age.
It is recommended to take medications only after consultation with a doctor and a thorough examination. This is necessary to prevent the occurrence of cancer.
Omez can be purchased at a pharmacy even without a doctor’s prescription. But it is necessary to consult if, in addition to medications, the patient additionally takes:
- Ampicillin.
- Phenytoin.
- Disulfiram.
- Diazepam.
- Blood thinners.
- Nutritional supplements that contain iron.
- Medicines for the treatment of AIDS.
You should immediately consult a doctor if, after taking Omeprazole, swelling of the tissues in the throat, face or tongue, breathing problems, or allergies occurs.
It is advisable to call an ambulance if the following problems arise: suffocation, dizziness, severe cough, involuntary contraction of muscle tissue, spasms.
It is also necessary to stop taking the drug if you have diarrhea, nausea, pain in the abdomen, sneezing, swelling of the nasopharyngeal tissue, or a sharp increase in temperature. In addition, headaches, bloating, and vomiting may occur.
Contraindications to the use of the drug
There are cases in which the use of a drug such as Omez is strictly prohibited. For example:
- Individual intolerance to the ingredients of the drug.
- Impaired functioning of the liver and kidneys. These organs belong to the excretory system, so when taking medications, a large load is directed specifically at them. Chronic or acute diseases may occur.
- Children. In general, it is not recommended to use Omez for children of any age, but there are a number of examples in which the doctor believes that there are much more beneficial effects than side effects.
It works especially well when using Phosphalugel. It protects the walls of the stomach from the negative effects of the aggressive components of Omez.
Side effect
Any drug has both positive and negative effects. It is especially dangerous if these consequences cannot be changed. Reactions from the central nervous system are possible.
These could be headaches, dizziness, insomnia, and in extreme cases, even hallucinations. The gastrointestinal tract may also react negatively.
Pain, vomiting, diarrhea or constipation occur. Additionally, muscles may weaken, sweating may increase, and rashes may appear on the skin.
This drug helps to cope with dysfunction of the stomach and restore its normal functioning.
It is important to follow the recommendations of your doctor, take medications to relieve symptoms, and take a break if necessary.
Taking omez without a break is not entirely the right decision; it should be used to prevent the occurrence of seasonal exacerbations. It is able to protect the mucous membrane of the stomach and duodenum.
Source: https://jeludokbolit.ru/vse-pro-omez/kak-dolgo-prinimat-omez-bez-pereryva.html
Side effects when taking the drug
The medication has a fairly impressive list of unpleasant side effects that are possible after administration orally or intravenously. They happen extremely rarely and disappear immediately after stopping use.
Most often, allergic manifestations were noticed in the form of a rash or urticaria. Omez is allowed to be purchased at a pharmacy without a specialist prescription.
The instructions list the following side effects:
- Problems with stool. Everyone may experience unpleasant symptoms differently. The drug can cause severe diarrhea and encourage frequent bowel movements. It can also cause a complete lack of stool and constipation;
- Painful sensations, bloating, heaviness in the abdomen;
- Severe nausea, rarely vomiting;
- Flatulence, severe gas formation;
- Liver disorders;
- Changed taste in the food the patient eats;
- Liver functions are impaired. In some cases, icteric hepatitis is possible;
- Stomatitis;
- Dry mouth;
- Disturbances in the composition of the blood. Rarely – leukemia;
- People exposed to severe emotional stress and with a weak nervous system may be susceptible to mental health problems. There is a possibility of depression, excessive excitability, aggressiveness, nervousness, breakdowns;
- Patients with a diseased liver are susceptible to hepatic encephalopathy;
- General weakness of the body, malaise;
- Deterioration of vision;
- Hair loss;
- Allergic reactions. Severe itching, redness on the skin and other manifestations of allergies;
- Possible swelling of the body;
- Increased sweating;
- Cysts in the stomach.
These side effects occur extremely rarely. If they appear, you should consult a doctor and change this medicine to another.
If undesirable effects are minor, they may be alleviated and symptoms may be relieved. The doctor may reduce the dosage or replace it with similar medications.
In case of allergic reactions to the products, you must immediately stop taking the capsules.
Features of the use of omeza D
Omeprazole is included as a component in other drugs used in gastroenterology. These include omez D. This is a complex drug that contains, in addition to omeprazole, domperidone (hence the added letter “D” in the name).
Effects
The medicine has a variety of effects:
- reduces nausea and vomiting;
- increases the tone of the esophageal sphincter;
- enhances peristalsis and accelerates emptying of the duodenum;
- improves digestion.
Indications
Omez D is recommended to be taken primarily for the following pathologies:
- erosive-ulcerative esophagitis, in which, due to weakness of the esophageal sphincter, gastric contents are thrown into the esophagus, which causes heartburn, cough, and sour belching;
- dyspepsia accompanied by symptoms of heartburn.
Side effects
More often they occur when the recommended dose and duration of treatment is exceeded, liver and kidney diseases. Headache, visual disturbances, dizziness, drowsiness, depressed mood, and weakness may occur. Changes in taste, nausea, vomiting, pain and gas formation in the intestines, and unstable stool may also develop.
With prolonged use in the stomach, due to suppression of the secretion of hydrochloric acid, benign cysts can form, which disappear after discontinuation of the drug. On the part of the skin and the muscular-articular system, skin itching and rash, muscle and joint pain are possible.
Occasionally, fever, sweating, swelling, and changes in blood tests are observed. Against the background of liver diseases, hepatitis and jaundice are possible. It must be remembered that with constant use, addiction develops and the effectiveness of Omez D decreases. The doctor will select a drug with a similar effect.
Omez D, in addition, can give specific side effects:
- abdominal pain due to cramps;
- extrapyramidal disorders.
If side effects occur, you should consult your doctor, who will tell you how to take Omez D correctly or replace it with another medicine.
Contraindications
These drugs are potent and have serious contraindications:
- intolerance to components;
- age up to 12 years;
- pregnancy and breastfeeding;
- gastrointestinal bleeding, intestinal obstruction;
- pituitary adenoma.
Important Notes
Only for strict indications is it prescribed to the elderly, patients suffering from liver and kidney diseases, since the elimination of the drug slows down and symptoms of overdose may occur. It is advisable to undergo an FGDS before and after treatment to exclude oncology and to objectify the scarring of the defect. For reflux esophagitis, a biopsy and x-ray examination are prescribed.
How to use
In case of exacerbation of a chronic disease, use it for about a month, after which the dose is reduced according to medical recommendations. For chronic diseases, to relieve persistent heartburn, it is better to take it in courses, alternating with other antacids. For pancreatic tumors, it is used under the supervision of the attending physician for 3–5 years.
Overdose
Characterized by nonspecific symptoms of poisoning: Disorientation, nausea, vomiting, drowsiness, arrhythmia. After gastric lavage and taking adsorbents, immediately consult a doctor.
Interaction with other drugs
When treating various diseases of the gastrointestinal tract, an integrated approach is possible.
Omez interacts with other drugs in different ways:
- The simultaneous use of Omez and De-Nol is permitted if prescribed by the attending physician
with De-Nol. The simultaneous use of these two drugs is permitted if prescribed by the attending physician. Sometimes they are part of the same treatment regimen; - With Diclofenac. It is possible to combine medications. Omez is able to protect the stomach from the harmful effects of diclofenac;
- Omez is compatible with the drug Concor;
- It is allowed to take Salofalk and Omez at the same time;
- The simultaneous use of Omez and Trimedat will not bring any complications;
Omez is often prescribed by doctors when using antibiotics. This is necessary to protect the stomach from the negative effects of antibacterial agents on the stomach.
Effects of the drug
Omez is a medicine with multifaceted action.
Antisecretory action
The drug blocks at the molecular and enzymatic level an already synthesized portion of hydrochloric acid. The secretion of gastric juice in response to food intake decreases. As a result, there is a decrease in acidity, a decrease in pain, nausea, and heartburn.
Cytoprotective effect
Protects cells from further damage from excess hydrochloric acid. At the same time, it promotes the healing of the damaged surface of the stomach.
Bactericidal effect
Destroys the bacteria Helicobacter pylori, which causes gastritis and peptic ulcers. Also kills other microbes that cause stomach diseases.
Conditions and periods of storage of the medicine
This medication is approved for sale without presenting a prescription from a doctor to the pharmacist. It should be stored in a very dry, dark place and out of reach of children.
The recommended storage temperature is room temperature, not exceeding twenty-five degrees. The capsules will be stored for three years. Liquid for solutions and injections is stored for no more than two years.
It is not recommended to take the medicine after its expiration date. This can harm the body and lead to complications.
Price for the drug Omez
The price of the product is quite affordable. You can purchase it both in a regular pharmacy and in an online store.
The price varies depending on the dosage, concentration, number of tablets inside and type of medicine:
- Capsules of 10 milligrams – about 100 rubles (30 pieces);
- Thirty capsules of 20 milligrams cost about 200 rubles ;
- Omez D. Thirty capsules - approximately 250 or more rubles ;
- Omez Insta. In the amount of five pieces. Can be purchased for 80 rubles ;
You can find out the exact price directly in your city at the pharmacy.
Analogues of the drug
The medicine has analogues both Russian and foreign. You should not choose an analogue without consulting a specialist.
The following Omez substitutes exist:
- Omeprazole;
- Nolpaza;
- Omecaps;
- Gastrozol;
- Demeprazole;
- Ultop;
- Chrismel;
- Omezol;
- Ranitidine;
- Oranthol;
- De Nol.
Ultop
Ornatol
Ranitidine
Omeprazole
Nolpaza
Gastrozol Omezol Demeprazole
De-Nol
Prices for these medications will vary depending on who produces the product.
Omez and Nolpaza
The effects of these drugs are approximately the same. They both help the body reduce hydrochloric acid levels. They also reduce symptoms of serious gastrointestinal ailments.
Nolpaz contains an active substance. It's called Pantoprazole. The advantage of Nolpaza is that the effect of this drug on the body sometimes occurs more quickly than that of Omez.
Omeprazole
The therapeutic effect is similar. The difference between the analogue and the original is only in additional components. The manufacturer is also different. The analogue contains the maximum content of the active ingredient.
There is much less of it in Omez, but thanks to its additional substances, the likelihood of side effects is minimized.
Omeprazole has a more affordable and lower price.
De Nol
This is an antiulcer medicine. Acts in the same way as Omez. The difference is the presence of bismuth subcitrate.
Omeprazole side effects with prolonged use
"Omeprazole" is a medicine that is produced on the basis of chemical components.
The main effect of the drug is to reduce the secretion of gastric glands. After entering the digestive organ, the capsule will dissolve, releasing an antisecretory substance that begins to work immediately after interaction with the contents of the environment.
This usually occurs within the first 20 minutes after taking the drug and continues for 24 hours.
Action of Omeprazole
In order to understand why the drug is effective in treating these diseases, you need to understand how it works. Here's what the instructions for use say about this. If we talk about the mechanism of its action , then it is a proton pump inhibitor.
Once in the acidic environment of the stomach, Omeprazole activates its healing properties. Namely: it suppresses the production of hydrochloric acid and also makes it less active.
This happens due to the fact that the active substance of the drug penetrates special cells of the stomach, which are responsible for the production of this acid.
In these cells, it is activated and begins to regulate the production of gastric juice and pepsin, a substance that breaks down proteins.
In addition, the drug also has a bactericidal effect . It destroys Helicobacter pylori bacteria. It is these microorganisms that provoke the formation of stomach and duodenal ulcers. Therefore, Omeprazole is always prescribed in the treatment of these diseases. And judging by the reviews, it was very successful.
Treatment with Omeprazole is also effective for reflux ulcerative or erosive esophagitis, that is, for pathological release of stomach contents into the esophagus. When taken in a timely manner, this drug significantly reduces the destructive effect of hydrochloric acid and restores the pH of gastric juice.
Brief information about Omeprazole
This antiulcer drug is successfully used in the treatment of any inflammatory processes in the stomach. The mechanism of its action is that Omeprazole neutralizes excess acid in gastric juice, bringing it back to normal, and also reduces the production of new hydrochloric acid. This creates pleasant conditions for the healing of ulcerative lesions and erosions on the gastric mucosa.
Take the drug only once a day, preferably before breakfast. The effect of one tablet or capsule lasts a whole day. After you stop taking the medicine, it continues to work for several more days.
Indications for the use of Omeprazole are:
- Stomach and duodenal ulcers, including those caused by medications, Helicobacter pylori bacteria and stress;
- Reflux esophagitis;
- Gastrinoma;
- Gastroesophageal reflux
Diseases for which Omeprazole is used
Some indications for taking the drug Omeprazole have already been mentioned above. Why else is it prescribed? This is what the list in the instructions for use of this drug looks like:
- peptic ulcer of the stomach and duodenum, both in the acute stage and for prevention purposes, in the remission stage, including ulcers caused by Helicobacter pylori,
- stress ulcers of the stomach and duodenum,
- gastropathology while taking NSAIDs,
- reflux esophagitis, including erosive,
- polyendocrine adenomatosis, that is, the development of tumors of the endocrine glands, most often the parathyroid and pancreas,
- Zollinger-Elisson syndrome is when tumors develop in the stomach, pancreas and duodenum,
- systemic mastocytosis is a condition where ulcers of the digestive tract develop due to excess mast cells,
- stress ulcers of the digestive tract.
In addition to these conditions, Omeprazole has found its use in the treatment of gastritis and in the treatment of heartburn. As for gastritis, only diseases with high acidity are treated with this drug. And if the acidity is normal or low , then it is better to avoid using this remedy, as this can cause the appearance of atrophic gastritis with zero acidity.
As for heartburn, self-administration of the drug is only possible if urgent help is needed. In general, treatment should be carried out under the supervision of a doctor (the drug is part of the group of prescription drugs). For heartburn, the course of treatment is 14 days, and the effect is achieved in 4–5 days.
Interaction of Omeprazole with other drugs
Omeprazole can change the effect of any drug (Ketoconazole, Itraconazole, Ampicillin, iron salts, etc.), the activity and absorption of which depends on the pH of the stomach.
Drugs that are transformed in the liver (Warfarin, Diazepam, Phenytoin, etc.) may, when interacting with Omeprazole, break down more slowly, increasing their concentration in the blood and tissues. Omeprazole also slows down the release of tranquilizers from the body (Sibazon, Diazepam, Elenium). In these cases, it may be necessary to reduce the dose of these medications.
Omeprazole may enhance the effect of indirect anticoagulants and anticonvulsants (coumarins, Diphenin). When taking Clarithromycin and Omeprazole simultaneously, the effects are mutually enhanced.
Omeprazole enhances the negative effect of other drugs on the hematopoietic system.
Composition and release forms
The main active ingredient of this drug is Omeprazole. It also includes auxiliary substances, such as:
- glycerol,
- gelatin,
- nipazole,
- nipagin,
- titanium dioxide,
- sodium lauryl sulfate,
- dye E 129,
- purified water for injection.
The drug is available in two dosage forms. These are enteric capsules and tablets, also called pellets. The dosage of the active substance is the same in both capsules and tablets.
It is 10, 20 or 40 mg. Both tablets and Omeprazole capsules are packaged in blisters and cardboard packaging. Sometimes some manufacturers also pack capsules in polymer jars. This is what Omeprazole looks like at the pharmacy.
You can see a photo of the packaging here.
In addition to forms for oral use, there is also another form - this is a powder for preparing a solution for injection. It is sold in 40 mg bottles. The package contains 5 of these bottles.
Source: https://kcdc.ru/lekarstva/omeprazol-sostav.html