Characteristics of Nolpaza
The active ingredient in this medicine is pantoprazole sodium. Depending on the dosage, 1 tablet may contain 20 or 40 mg. Mannitol, calcium stearate, and crospovidone are used as auxiliary components. The medication is available in the form of round tablets in a soluble coating. When the medicine enters the body, it reduces the production of gastric juice, thereby reducing the concentration of hydrochloric acid. Prescribed most often for peptic ulcers of the stomach or duodenum.
Nolpaza and Omeprazole are drugs to reduce the amount of hydrochloric acid in the stomach.
"Nolpaza"
The main component of this medicine is pantoprazole sodium (20 or 40 mg depending on the dosage). Also additionally present: mannitol, crospovidone, calcium stearate, etc.
The medication itself is available in the form of round tablets in a soluble coating.
Principle of action: when Nolpaza enters the body, it reduces the production of gastric juice, thereby reducing the dangerous effects of the acid contained in it.
This drug is prescribed mainly for the treatment of stomach and duodenal ulcers.
Contraindications for Nolpaza:
- Intolerance to the components of the drug.
- It is recommended to take it with caution for pregnant women and people with deficiencies in the functioning of the liver and kidneys.
- Prohibited under 18 years of age.
The method and dosage of administration are determined by the doctor and can vary from 20 to 40 mg . The medicine is taken before meals and washed down with plenty of water.
During treatment with this drug, certain negative consequences may occur:
- Increased gas formation, problems with stool, nausea, vomiting.
- Increased liver enzymes.
- Dizziness, headaches, worsening mood.
- Other allergic reactions may occur.
In case of overdose, no negative consequences were identified.
Comparison of Nolpaza and Omeprazole
To choose a drug, you need to compare the properties of both medications.
Nolpaza is most often prescribed for peptic ulcers of the stomach or duodenum.
Similarities
The mechanism of action of drugs is similar. For this reason, they can be used to treat stomach ulcers. The group to which the drugs belong is common: they are proton pump inhibitors that regulate the amount of hydrochloric acid in the patient’s body. The adverse reactions that occur during use are also similar: both drugs can cause an allergic reaction, stool upset, headache, dizziness, sleep problems and a general deterioration in well-being, bad mood.
Differences
The active ingredients differ. For this reason, the contraindications will also be different: a person with an individual intolerance to one component may choose a medicine. The release forms also differ - Omeprazole has a larger number of them.
Omeprazole is used to treat a wide range of pathologies: in addition to peptic ulcers, it can be prescribed for inflammatory processes in the pancreas, gastritis, bloating, heartburn and for the prevention of these diseases. With Omeprazole, in case of overdose, undesirable effects are observed that were not noticed when using Nolpaza. Nolpaza will begin to act only after 3 hours; It will take 20-30 minutes for the effect of using Omeprazole to appear.
Omeprazole is used to treat a wide range of pathologies, in addition to peptic ulcers.
Which is cheaper?
Since Nolpaza is produced abroad, the cost of this product is higher: you will have to pay from 200 to 600 rubles for packaging. Omeprazole is produced in Russia, so its price is lower - only 30-150 rubles per pack.
Nolpaza or Omez – which is better?
Manufacturer: Dr.
Reddy,s (India) Release form: capsules
Active ingredient: omeprazole
Nolpaza and Omez are in the same pharmacological group and are proton pump inhibitors. They inhibit the secretory function of the gastric glands and give an equivalent treatment result. Medicines are used for gastritis and ulcerative processes of the stomach and duodenum.
But the analogue of Nolpaza Omez gives quick results. It will be more effective if it is necessary to reduce pathological symptoms in a short time. To achieve a prolonged effect of the drug, it is better to use Nolpaza. According to doctors, it is better to use Omez for the treatment of gastritis, and Nolpaza for gastric ulcers.
According to experts, Omez deserves more confidence as a drug that has undergone more clinical trials and has experience of use in the treatment of children.
Patient reviews
Alexandra, 33 years old, Serpukhov: “Before pregnancy I was treated with Nolpaza, but when I became pregnant, I had to look for a replacement. The doctor prescribed Omeprazole. The medicine turned out to be effective and good. The big advantage was the quick action: you didn’t have to wait for relief for 3 hours, as when taking Nolpaza. The lower cost of the drug was also an advantage. I recommend".
Anna, 28 years old, Novosibirsk: “I used Nolpaza to treat duodenal ulcers, since Omeprazole did not suit me. The product is good, effective, improvement in the condition is noted soon after starting to take it. There were no side effects; I took it strictly according to the instructions of the attending physician. The only negative is the price. The product is imported, so it’s not cheap, I had to spend a lot of money on the course of therapy.”
Igor, 46 years old, Kazan: “The need for Omeprazole injections appeared in my son at the age of 12 - due to poor nutrition and consumption of harmful foods, the child developed gastritis. The injections were unpleasant, but effective - my health quickly improved after the injections. We completed a course of treatment. Now the child feels well. I recommend it because... The medicine is inexpensive and effective.”
Nolpaza or Omeprazole – which is better, what is the difference
Manufacturer: Sintez (Russia)
Release form: capsules
Active ingredient: omeprazole
Nolpaza and Omeprazole are used for medicinal purposes to eliminate the manifestations of stomach diseases. Despite the identical indications for the use of drugs, they have a number of differences:
- by manufacturer and cost of medicines;
- active substance;
- release form;
- time of onset of effect;
- interaction with other drugs.
It is more rational to replace Nolpaza with Omeprazole in the acute course of the inflammatory process, in particular in pancreatitis. Ulcers or erosions of the gastric mucosa respond better to treatment with Nolpaza. In this case, it will be more effective, and the reduction in symptoms of the disease will be noticeable within a week.
According to doctors, patients taking Nolpaza recover faster and have a long period of remission.
Nolpaza or Rabeprazole – which is better?
Manufacturer: FP Obolenskoe (Russia)
Release form: tablets
Active ingredient: rabeprazole
Rabeprazole and Nolpaza belong to the same pharmacological group and are proton pump inhibitors. The drugs are active against Helicobacter pylori, which causes gastric ulcers. The analogue Rabeprazole is prescribed in combination with antibiotics to combat this type of bacteria.
A cheaper substitute, Rabeprazole, increases the effectiveness of antibacterial drugs. This property of the drug is used by doctors to reduce the dosage of antibiotics and preserve normal intestinal microflora.
Which drug will be the best depends on the development of the disease, concomitant chronic diseases of internal organs, and the age of the patient. The advantage of prescribing Nolpaza or Rabeprazole will be decided only by a doctor.
Nolpaza or Controloc
Manufacturer: Takeda (Germany)
Release form: tablets
Active ingredient: pantoprazole
Both analogues are proton pump inhibitors and are actively used to treat gastrointestinal diseases.
Controloc is an original drug and has greater activity of the active substance. Its use is more preferable for the treatment of gastric reflux, and Nolpaza for peptic ulcers and mucosal erosion.
Nolpaza or Nexium – which is better?
Manufacturer: Astrazeneca (Sweden)
Release form: tablets
Active ingredient: esomeprazole
Nexium is an analogue of a new generation of drugs for the treatment of gastrointestinal diseases and is more effective in esophagitis, as well as in other inflammatory pathologies of the gastrointestinal tract. According to reviews from practicing gastroenterologists, the use of Nolpaza is more justified in the treatment of ulcerative pathologies of the stomach and duodenum.
Differences between Nolpaza and Omeprazole
To understand what the difference is between the drugs and how they are interchangeable, let’s consider them from the point of view of their main characteristics:
The price is produced in Slovenia, the cost of the package is approximately 200-600 rubles , depending on the dosage and the number of tablets in the pack. "Omeprazole" is produced in Russia, Serbia and Israel, its price ranges from 30-150 rubles .
Active ingredient
Studies have shown that the intensity of the acticeretory effect of the proton pump inhibitor omeprazole exceeds that of pantoprazole. The time to achieve maximum effect for pantoprazole is almost three times longer than for omeprazole.
Release form
Omeprazole is available in a single form - gelatin-coated capsules. Nolpaza is available in the form of film-coated tablets.
How long does it take for the effect of taking the drug to appear?
The effect of Omeprazole begins, depending on the characteristics of the body, about half an hour to an hour after administration. Nolpaze takes about two hours to reach its maximum concentration in the blood plasma.
Contraindications
The list of contraindications for prescribing Omeprazole is not too wide and includes intolerance to the components of the drug, childhood, pregnancy and breastfeeding (treatment is possible, but it is necessary to switch the baby to formula). Contraindications to taking Nolpaza are:
- intolerance to the components of the drug;
- age under 18 years;
- dyspepsia (neurotic genesis);
- malignant formations in the gastrointestinal tract;
- simultaneous administration with the drug "Atazanavir".
Interaction with other drugs
As the history of observations of patients treated with Omeprazole shows, long-term use of 20 mg per day did not have a significant effect on most drugs.
However, it is undesirable to take the drug simultaneously with those drugs, the absorption of which directly depends on the pH value. In this case, Omeprazole will reduce their effectiveness. “Nolpaza” has an absolutely similar effect. It can be taken simultaneously with the following drugs without any risk:
- Cardiovascular drugs (Digoxin, Nifedipine, Metoprolol);
- Antibiotics for the treatment of the digestive system (“Amoxicillin”, “clarithromycin”);
- Oral contraceptives;
- Non-steroidal anti-inflammatory drugs;
- Drugs for the treatment of the endocrine system (“Glibenclamide”, “Levothyroxine sodium”);
- Anxiolytics (“Diazepam”);
- Antielliptic drugs (“Carbamazepine” and “Phenytoin”);
- Immunosuppressants (Cyclosporin, Tacrolimus).
Side effects
The list of possible side effects looks quite impressive, but almost all of them occurred in isolated cases, in seriously ill patients, while taking potent drugs.
Disorders of the digestive system (stool, nausea, pain, gas formation) are relatively common. Much less often you can observe such reactions as sleep disturbances, vertigo, ringing in the ears, swelling of the extremities, and allergic skin rashes.
As for Nolpaza, about ten percent of drug prescriptions result in headaches, abdominal pain, constipation, diarrhea, and gas. Much less frequently, in approximately every hundredth patient, the following occurred:
- increased drowsiness;
- insomnia;
- blurred vision;
- dizziness;
- allergic skin reactions;
- weakness;
Overdose
Cases of Omeprazole overdose have been observed quite rarely, with the following symptoms: confusion, blurred vision, dry mouth, headaches, nausea, arrhythmia. The instructions for use of Nolpaza indicate that no cases of overdose in humans have been identified. However, in both cases, symptomatic treatment is recommended, since hemodialysis is not effective.
Concluding all of the above, it can be noted that the difference between the two drugs, although it exists, is not too significant. "Omeprazole" and "Nolpaza" differ quite greatly in price, and also differ in the active substance in the composition. Moreover, the mechanism of their work in the body is completely identical.
Omeprazole was released onto the market much earlier, its effect on the body has been studied much better. At the same time, there have been no cases of overdose of Nolpaza; side effects from its use are also less common.
Nolpaza or Pantoprazole – which is better?
Manufacturer: Lekvalis (Russia)
Release form: tablets
Active ingredient: pantoprazole
Nolpaza analogue 20 mg Pantoprazole is a drug used to treat peptic ulcers, reflux esophagitis, Zollinger-Ellison syndrome. The drug has a prolonged effect. Dyspeptic symptoms (nausea, heartburn, abdominal pain) are relieved within 1–2 days.
If the exacerbation of the ulcerative process is severe, then Pantoprazole will be the best treatment.
Before prescribing a course of therapy, it is necessary to exclude an oncological process, since therapeutic measures using a Pantoprazole analogue blur the clinical picture of the disease. According to doctors, it is well tolerated by patients and gives positive results.
