Comparison of the effectiveness of De-nol and Ulcavis
The effectiveness of De-nol is quite similar to Ulcavis - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of De-nol is more pronounced, then using Ulcavis even in large doses will not achieve this effect.
Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for De-nol and Ulcavis. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Comparison of composition and mechanism of action
Ulkavis and De-Nol contain the same active ingredient - bismuth tripotassium dicitrate.
That is, these drugs are analogues. The active component determines the mechanism of action of the drug. Let's compare Ulkavis with De-Nol. These drugs are similar in many ways because they have the same active ingredient (bismuth oxide). Its content is 120 mg in 1 capsule. They are also classified into one medicinal group - drugs used for diseases of the digestive tract.
What De-Nol and Ulcavis have in common is their pharmacological form (both drugs are available in tablet form), as well as the method of administration - the tablets are taken orally, without chewing and with liquid. The dosage is selected individually depending on the pathology and its severity.
Since the active substance is the same, the mechanism of action is similar. They have astringent, antiseptic, antimicrobial and gastrocytoprotective effects.
De-Nol and Ulcavis are prescribed for the same pathological conditions.
Indications for their use are:
- peptic ulcer (especially in the acute stage);
- pathologies of the digestive tract associated with the action of the Helicobacter bacteria;
- gastritis (acute or chronic);
- poisoning with non-steroidal anti-inflammatory drugs;
- dyspepsia not associated with organic pathologies of the digestive system;
- irritable bowel syndrome.
Such medications have the same contraindications and side effects. Ulcavis and De-Nol have a minimum of contraindications. They are not prescribed for individual sensitivity to the substances that are part of them, or for severe kidney pathologies. It is not recommended to take medications during pregnancy, breastfeeding, or in childhood. Side effects include some dyspeptic disorders, which occur as a result of addiction to the medications and go away on their own. Allergic reactions may occur.
What is the difference between the drugs? The main difference is the manufacturer and price. De-Nol is a more expensive product. The drug is produced in the Netherlands. That's why it's not cheap:
De-Nol 32 tablets | 360 rub. |
De-Nol 56 tablets | 550 rub. |
De-Nol 112 tablets | 940 rub. |
Ulcavis is produced in Slovenia. Its prices:
Ulcavis 28 tablets | 215 RUR |
Ulcavis 56 tablets | 380 rub. |
Ulcavis 112 tablets | 640 rub. |
In terms of composition, De-Nol and Ulkavis are analogues. There is a slight difference in the presence of auxiliary components , but it does not affect the overall effect of the drugs. Pharmacies also have substitutes for De-Nol and Ulcavis - Novobismol and Escape, which also help well with diseases of the digestive system. The attending physician prescribes this or that drug.
Comparison of safety of De-nol and Ulcavis
The safety of a drug includes many factors.
At the same time, in De-nol it is quite similar to Ulcavis. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in De-nol, as well as in Ulcavis, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, De-nol does not have any risks when used, just like Ulcavis.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using De-nol and Ulcavis.
What's better
Patients often ask doctors the question: what is better to choose. Both medications are prescribed depending on the characteristics of a particular case of illness. It is better to combine with antibiotics and other groups of drugs.
Clinical studies have confirmed the equal effectiveness of the medications in question. Manufacturer and cost vary. Novobismol is more accessible, so many people prefer it.
Which medicine is better
After a full course of De-Nol, improvement occurs - inflammation was suppressed, and the activity of the pathogenic bacteria decreased. This was confirmed by the results of respiratory testing.
After Novobismol there is an improvement, but not to the same extent as after De-Nol, so I have to continue treatment with additional drugs.
Comparison of addiction between De-nol and Ulcavis
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in De-nol is quite similar to the similar values in Ulkavis. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in De-nol the meaning of the “syndrome” is quite small, however, the same as in Ulkavis.
Reviews from patients about the tablets "De-Nol" and "Novobismol"
Most patients were able to get rid of ulcers and gastroduodenitis with the help of these medications. Within a short time, a therapeutic effect occurs. In most cases, there are no side effects from the medicine. Both products are easy to use. The medicine contains bismuth, which will help to cope with stomach ulcers and erosion as quickly as possible.
You can also hear negative reviews about medicines. Some patients complain that they experience diarrhea and nausea during treatment. This may be due to gastrointestinal problems caused by Helicobacter pylori.
And yet, what is better - Novobismol or De-Nol? The drugs have identical composition. The cost differs. For Novobismol tablets you will have to pay about 350 rubles. At the same time, the price of De-Nol is 500 rubles. Which drug should you choose? The decision should be made together with your doctor.
Comparison of side effects of De-nol and Ulcavis
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
De-nol's side effects are almost the same as those of Ulcavis. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of De-nol are similar to Ulcavis: how quickly the body recovers after taking it and whether it recovers at all.
De-Nol, composition
The main substance of the medicine is bismuth. Once in the stomach, it settles without dissolving and forms a protective film, covering ulcers and erosions. Helps produce prostaglandin “E”, activates mucus production. After a ten-day course, relief and healing of the mucous membrane in the damaged areas occurs.
De-Nol
Indications
In accordance with the instructions, prescribing the medication is advisable for the following diagnoses:
- ulcers in the stomach, intestines - damage to the mucous membrane is formed under the influence of bacteria, exposure to bile or gastric juice;
- acute or chronic gastritis, duodenitis;
- irritable bowel syndrome;
- dyspeptic symptoms.
Contraindications
Bismuth-based medications are contraindicated for:
- kidney disorders;
- pregnancy;
- hypersensitivity to the components of the composition;
- childhood;
- lactation.
Note! A common side effect of the drug is darkening the stool. This is not at all dangerous; after completing the course of treatment, this symptom goes away spontaneously.
Mode of application
The medicine should not be taken for more than two months. The tablet is taken half an hour before meals. The drug is prescribed in combination with other medications for adults and children over 14 years of age. The standard dose is 4 tablets in 2-4 doses. Course 1-2 months. If you need to continue using the drug, take a break of at least two months.
Analogs
Name | Manufacturer |
Vis-Nol | Ukraine, capsules 30 pieces |
Gastro-Norm | Ukraine, tablets 100 pieces |
Ulcavis | Slovenia, 56 tablets |
2-3 reviews
I think De-Nol is a good remedy; it helped me cope with incipient gastritis. It really works and has a small list of side effects. It is advisable to take it in combination with other medications. With monotherapy, the effect is noticeably reduced.
Dmitry, 26 years old
“De-Nol” helped me quickly relieve a bad feeling, the doctor prescribed it. I am very pleased with the medicine.
Irina, 32 years old
Price
The cost of the medicine is on average 520 rubles. for 56 tablets.